Pathophysiology – Cystic Fibrosis Essay Assignment

Pathophysiology – Cystic Fibrosis Essay Assignment

Cystic Fibrosis Article


1.Find an article on a genetic disorder (use article above about Cystic Fibrosis), and

1.1. Summarize in two or three paragraphs the genetic component causing the disorder and any multifactorial inheritance components that may contribute to the disorder.Pathophysiology – Cystic Fibrosis Essay Assignment

1.2.Discuss the usual age of disease onset and if the sex-specific threshold model fits the disorder.

1.3.What education could you present to high-risk patients to reduce the risk of disease onset if a multifactorial component exists.Pathophysiology – Cystic Fibrosis Essay Assignment




  1. Genetic screening has become widely available to the public including prenatal screening of the fetus in utero to screening adults for genetic disorders, such as Parkinson's disease and breast cancer. 2.1.Share your thoughts on the legal, ethical, and social implications that may be related to genetic screening.Pathophysiology – Cystic Fibrosis Essay Assignment

2.2.How would you educate your patient that is considering having genetic screening?

Answer each question separate.

Use next reference for both articles Pathophysiology: The Biologic Basis for Disease in Adults and Children

McCance, K. L., Huether, S. E., Brashers, V.L., and Rote, N. S. (2013). Pathophysiology: The biologic basis for disease in adults and children (7th ed.). St. Louis: Mosby Elsevier. ISBN-13: 9780323088541

Total of 3 references for each discussion question.Pathophysiology – Cystic Fibrosis Essay Assignment

Cystic Fibrosis

Cystic fibrosis (CF) is a genetic disease that results in thick, sticky mucus that interferes with breathing and digestion, among other bodily functions.Pathophysiology – Cystic Fibrosis Essay Assignment

What is cystic fibrosis (CF)?

Cystic fibrosis (CF) is a genetic disease that causes sticky, thick mucus to build up in organs including the lungs and the pancreas. In a healthy person, mucus that lines organs and body cavities, such as the lungs and the nose, is slippery and watery. In people with CF, thick mucus clogs the airways, making breathing troublesome. Its blockage of the ducts in the pancreas causes problems with digesting food. Babies and children with CF may not be able to absorb enough nutrients from food. Other organs that CF affects are the liver, sinuses, intestines, and sex organs. CF is a condition that is chronic (long-lasting) and progressive (getting worse over time).

How common is cystic fibrosis?

Among white children in the United States, the rate of CF cases is one in 3,500 newborns. CF affects about one in 17,000 black newborns and one in 31,000 newborns of Asian descent.Pathophysiology – Cystic Fibrosis Essay Assignment

What are the symptoms of cystic fibrosis (CF)?

Children with CF have the following symptoms:

  • Failure to thrive (inability to gain weight despite having good appetite and taking in enough calories)
  • Loose stools or oily stools
  • Trouble breathing
  • Recurrent wheezing
  • Frequent lung infections (recurrent pneumonia or bronchitis)
  • Recurrent sinus infections
  • A nagging cough
  • Slow growth

What causes cystic fibrosis?

CF is a disease that is passed through genes called the CFTR genes. People with CF inherit two faulty genes, one from each parent. The parents do not have to have CF. Many families do not have a family history of CF. In this case, the person with the faulty gene is called the carrier. About one in 31 people in the United States are carriers who are free of CF symptoms.Pathophysiology – Cystic Fibrosis Essay Assignment