Pathophysiology of Acute Renal Failure in Rhabdomyolysis Essay

Pathophysiology of Acute Renal Failure in Rhabdomyolysis Essay

A 28-year-old male presents to the primary care office for evaluation of left calf pain, swelling, and redness. He reports that this started one day ago and worsened today. He ran a 27-mile marathon 2 days ago and traveled for 3 hours in a car today. He reports slight pain on walking and a swollen red calf. He took Ibuprofen 600 mg twice today without relief. Patient reports being an experienced runner, running 3-5 miles daily. He trained for the marathon for 4 months. Patient also reports a history of exercise induced asthma and uses albuterol sulfate HFA as needed.Pathophysiology of Acute Renal Failure in Rhabdomyolysis Essay

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On physical exam patient appears in good health T 99 P 68 R 18 BP 118/78 wt. 175 lb, height 72 in. BMI 23.1. Heart rate is regular without murmurs, rubs, or gallops. Lungs clear bilaterally. HEENT WNL. Strength lower extremities +5 and DTRs + 2. Left calf erythematous, edematous, warm and tender on palpation. Pulses 3+.Pathophysiology of Acute Renal Failure in Rhabdomyolysis Essay

Two possible diagnoses were considered: deep vein thrombosis (DVT) and rhabdomyolysis.
Stat ultrasound of left leg to rule out DVT was ordered and read as normal
CBC WNLPathophysiology of Acute Renal Failure in Rhabdomyolysis Essay
Creatine Kinase (CK) 23,000 U/L (normal 24-170 U/L)
BUN and Creatinine WNL
A diagnosis of rhabdomyolysis was made.

1. Discuss the pathophysiology of acute renal failure in rhabdomyolysis.Pathophysiology of Acute Renal Failure in Rhabdomyolysis Essay